AOR and Quality
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AOR and Quality
The History of Innovation
In the short space of a decade, AOR has risen to become a leading provider of genuinely innovative nutraceuticals in North America with their Bottled Revolutions: groundbreaking, research backed orthomolecules and botanicals.
AOR released Canada's first defined pollen extract (Prostaphil-2), the first supplement developed to directly affect prostate structure by reducing the volume of the gland itself instead of simply relieving symptoms as with other conventional prostate herbals. It was the first company to bring a geniunely complete E-complex supplement in the form of Total E tocopherols and tocotrienols.
Other firsts include the intoduction of the world's first R(+)-lipoic acid supplement containing the genuine orthomolecular form rather than the racemic hybrid of natural R(+)- and synthetic S(-)-enantiomers found in conventional lipoic acid or alpha lipoic acid supplements; North America's first Menatetrenone (under the name Peak K2), the mammalian-specific vitamer form of vitamin K2 for bone health support; Benfotiamine, a lipidsoluble derivative of thiamine long used in Germany to relieve the symptoms of diabetic peripheral neuropathy; and the groundbreaking delivery of the revolutionary bone health mineral Strontium at a clinically-tested dose.
Priority: Results For You
AOR's formulations have always been designed with an overriding emphasis on ensuring that the final results deliver as promised. This begins with a careful review of the primary science on a supplement, insisting on solid science and real-world outcomes. Ingredients whose only scientific support comes from surrogate outcomes, mechanistic speculation, in vitro studies, or experimental conditions that don't reflect the real challenges of patients are eschewed in favour of the results of high quality evidence and clinical trials. The final formulation is then designed to reflect the clinical trials themselves, with doses, standardization, and forms of nutrients reflecting the original research.
Special care is taken with multiingredient supplements - a class of natural health product that is often subject to shoddy formulation. Supplements with multiple ingredients can and do work very well, - if they’re properly formulated.
Many companies approach the formulation of their products as if the object is to come up with the longest possible list of ingredients of interest to people with a particular health concern. In the process, basic issues around dosage, compatibility, stability, and mechanism of action are brushed aside in a rush to put out a pill which - from a quick glance at the label - appears to be the "broadest," most "comprehensive," most "all-inclusive" and "synergistically complete" product on the shelf.
So consistently good formulation requires both the best science, and the best motivations. Something has to provide the impetus to keep a supplement company poring over medical journals, combing through new research in search of new discoveries, and questioning the market's common formulation cliches.
AOR has built it's reputation for high quality and efficacy one supplement at a time, diligently pursuing optimal formulation from the primary research up.
Excellence in Quality Control
In the regulatory vacuum of the North American dietary supplement industry, quality control has always been a concern. Along with opening up the market to greater freedom of choice, the Dietary Supplements Health and Education Act (DSHEA) also had the unfortunate effect of deregulating the manufacture of dietary supplements. To date, the US Food and Drug Administration (FDA) has yet to implement Good Manufacturing Practice (GMP) regulations in the United States - and even when they do, DSHEA strongly limits the standards to which American dietary supplement companies can be held.
From the outset, AOR has maintained a process of self-imposed quality control, creating internal standard operating procedures (SOPs) that are modeled on the pharmaceutical industry's for purity and rigor. Formal, regulatory requirements for the manufacture of dietary supplements have now been brought into the Canadian industry by the new Natural Health Products Directorate (NHPD), using GMPs which are again modeled standards established for use in pharmaceutical labs. AOR operates its facilities under standards created to meet or exceed the requirements of this formal site licensing regime.
Furthermore, all AOR products and raw materials are subject to a regular and ongoing process of third-party analysis by independent analytical laboratories to ensure purity and potency. High performance liquid chromatography (HPLC) is the preferred technology for analysis of active ingredients and detection of contaminants.
This information courtesy of and copyright Advanced Orthomolecular Research. Used with permission.
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